Fig 1: Chrysin inhibits the expression of downstream malignant effectors via DGKa/FAK complex. (A)–(L) The indicated control or DGKa shRNA or 1 µmol/L PF562271-incubated ESCC cells were treated with 50 µmol/L chrysin. The intratumoral expression of C-MYC (A), cyclin D1 (B), survivin (C), SOX2 (D), NANOG (E), OCT4 (F), BMI1 (G), PKM2 (H), HKII (I), LDHA (J), GLUT1 (K), and the secretion of MMP9 in supernatant (L) were evaluated using quantitative ELISA assay. n.s, no significant difference. Error bars, mean ± SD of five independent experiments.